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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPG2 All Species: 7.58
Human Site: T3898 Identified Species: 16.67
UniProt: P98160 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98160 NP_005520.4 4391 468798 T3898 E A C G P D A T C V N R P D G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001099299 4392 468662 T3899 E A C G P D A T C V N R P D G
Dog Lupus familis XP_535371 2720 290354 Y2267 S T H S G S S Y T L A P E G A
Cat Felis silvestris
Mouse Mus musculus Q05793 3707 398275 S3254 P S M S G A G S Y L A L P A L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518520 1150 124768 R697 C F C M G V S R Q C A S S S W
Chicken Gallus gallus NP_001001876 4071 432826 V3618 T E G E A V S V P S F D E A G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001120939 3407 371297 Y2954 L F D G E D S Y I A Y P P L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001027037 4179 461773 C3702 G V C G A G R C E N T E N D M
Honey Bee Apis mellifera XP_393220 3382 373579 N2929 G P A I I T S N H I L Q P G V
Nematode Worm Caenorhab. elegans Q06561 3375 369033 N2922 G G L P P G L N S P D D V V E
Sea Urchin Strong. purpuratus XP_001186142 2326 251883 C1872 G V E Q C P T C E V N P C A N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.8 51.7 N.A. 72.7 N.A. N.A. 20.8 58.1 N.A. 45.2 N.A. 22.1 25.7 24.2 24.2
Protein Similarity: 100 N.A. 98.6 54.6 N.A. 77.8 N.A. N.A. 23.2 69.8 N.A. 57.4 N.A. 35.9 39.4 37.9 34.7
P-Site Identity: 100 N.A. 100 0 N.A. 6.6 N.A. N.A. 6.6 6.6 N.A. 20 N.A. 20 6.6 6.6 13.3
P-Site Similarity: 100 N.A. 100 13.3 N.A. 26.6 N.A. N.A. 13.3 13.3 N.A. 26.6 N.A. 20 26.6 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 10 0 19 10 19 0 0 10 28 0 0 28 10 % A
% Cys: 10 0 37 0 10 0 0 19 19 10 0 0 10 0 0 % C
% Asp: 0 0 10 0 0 28 0 0 0 0 10 19 0 28 0 % D
% Glu: 19 10 10 10 10 0 0 0 19 0 0 10 19 0 10 % E
% Phe: 0 19 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 37 10 10 37 28 19 10 0 0 0 0 0 0 19 28 % G
% His: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 10 0 0 0 10 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 0 0 0 10 0 0 19 10 10 0 10 10 % L
% Met: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 19 0 10 28 0 10 0 10 % N
% Pro: 10 10 0 10 28 10 0 0 10 10 0 28 46 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 10 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 10 0 0 0 19 0 0 0 % R
% Ser: 10 10 0 19 0 10 46 10 10 10 0 10 10 10 0 % S
% Thr: 10 10 0 0 0 10 10 19 10 0 10 0 0 0 10 % T
% Val: 0 19 0 0 0 19 0 10 0 28 0 0 10 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 19 10 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _